Are there any good alternatives to Accutane for cystic acne?

Doctor's Answers 2

Cortisone shots are but a temporary solution to acne; they target inflammed acne and quickly reduce its size. This can help for urgent acne management (before social events) and to reduce the likelihood of scarring from large, ruptured acne. Side effects, however, like dimpling from shrinking of the fat around the acne (from the steroid injection) is possible. Hence benefits vs risks of such injections should be weighed before employing its use.

Acne management should first and foremost consist of a good baseline skincare regimen. This includes the use of acidic toners, retin/differin gels for prevention, as well as benzyl peroxide or clindamycin gels for active acne.

Addition of procedures such as chemical peels, certain lasers and even more permanent solutions such as AGNES radio-frequency needle ablation of oil glands are all good-to-haves in further helping to manage acne resistant to topical therapy.

Oral medication such as antibiotics are a possible option too, but its use is to mitigate temporary flares of acne and is not a permanent solution.

The other oral medication available, accutane/isotretinoin, is a more permanent and quick way of acne management. This is particularly useful in severe acne (such as nodulocystic acne) or recalcitrant acne that fails to respond to the above other modalities. There is a risk of affecting one's cholesterol and liver, so a close follow-up with your doctor is required. About 70% of patients have a permanent resolution of their acne issues after the first cycle that can last 7 to 10 months, but some need a second or third round before their acne gives.

If you truly have cystic acne, a quick and swift approach to manage it is the best idea. This would involve topicals, some clinical treatments, as well as possible accutane. This will help prevent further breakouts and further scarring.

As you can see, acne management can be slightly complex and a multi-pronged approach is required.

Do feel free to get a proper physical consult so a proper plan can be drawn out for yourself. The sooner you manage the acne, the less the long term sequelae of untreated acne.

Cheers, and Merry Christmas,

Dr Shane Abucewicz Tan

For large cystic acne, really, I feel that Isotretinoin is the best option as it goes down to the pathophysiology of reducing oil secretion. Combining it with antibiotics would solve it systemically.

Cortisone injections is a directed therapy for large cystic acne, and there is the risk of skin dimpling due to poor technique.

I would also suggest that you consider carbon laser therapy which has shown some efficacy in reducing the severity of cystic acne in a study.

Seek the right treatment after discussing with your physician

Winston

Similar Questions

Are there any Accutane providers other than NSC in Singapore? Do antibiotics work for acne?

Thanks for the detailed summary. There’s no problem at all with seeing a GP to treat your acne – the treatment algorithm for acne is pretty standard. My pet peeve is only with clinics who overcharge based on having some sort of special super secret ingredient “miracle acne creams”, because the reality is that all effective topical creams contain well-known ingredients, and packaging it under their own brand shouldn’t give them the right to charge more, or “lock-in” patients to only using their creams.

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What is the cost of corticosteroid injection for cystic acne in Singapore? Is it effective?

Corticosteroid injections for cystic acne in Singapore costs about $50 – $200. Cystic acne happens when the infection that causes acne goes deep into your skin, creating a large, inflamed, tender pimple that’s full of pus. These deep lesions are more likely to scar. Steroid injections work by reducing the inflammatory reaction, and can potentially reduce the amount of damage/scarring caused by a large cystic acne. Corticosteroid injections take about 4 – 8 hours to start shrinking the cystic acne. Pain will improve too.

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