What are the benefits of getting a combination of Rejuran and dermal fillers as compared to getting only one type of treatment?

Doctor's Answers (1)

Yes, most physicians do combine both dermal fillers and skin boosters like Rejuran for overall skin rejuvenation and face contouring effect.

Rejuran, a new healing treatment made of polynucleotides (PN) and polydeoxyribonucleotide (PDRN) derived from salmon DNA, has been touted as the new facial aesthetic treatment that is both effective and helps in improving the skin’s own regenerative properties. Rejuran PN/PDRN is injected in the inner skin layer to kick start your skin’s physiologic regeneration processes and also biologically increase metabolic activity in the cells within the dermis layer (the fibroblasts), which stimulates the production of collagen.

Rejuran PDRN’s healing properties have several beneficial effects on the skin, as shown in their funded study:

  1. Improved skin elasticity
  2. Improved hydration
  3. Reduced fine lines and wrinkles
  4. Skin repair- with improved skin barrier function
  5. Skin normalization- thickening of the skin, regulation of oil production
  6. Improved skin colour tone and pigmentations
  7. Improved skin texture- pores refined

While dermal fillers help to restore volume loss of the face due to the ageing process that causes:

  • fat loss,
  • muscle atrophy, and
  • bone demineralization.

Dermal fillers are often used to restore volume on the:

  • cheeks,
  • temples,
  • foreheads, and
  • augmentation of the chin, jawline, and nose.

It is very common for a physician to approach one skin with multiple treatments to address various skin concern. I personally like to combine Rejuran PN/PDRN with lasers, PDO/PCL face thread lifts and non cross-linked HA fillers to have a synergistic effect (1+1 >2) on your skin.

However, do speak to your doctor prior to any minimally invasive procedure. I often avoid injecting Rejuran PN/PDRN into skin with prior treatments involving collagen stimulators or biostimulant fillers such as Ellanse, Radiesse, Sculptra and cross-linked HA fillers within a year as Rejuran PN/PDRN has been reported to react with these fillers causing granuloma formation.