Question
HA Fillers can be dissolved with hyalase, even after a year of placement. Several sessions may be required to achieve the desired outcome, and sometimes controlling the amount dissolved might not be possible. As such you may need to undergo the dissolving, then a touch up with fillers a few weeks later.
Other fillers such as Non-HA fillers (like Radiesse, sculptra and Ellanse) are not really affected by hyalase and cannot really be dissolved.
Cheers!
Dr Shane Tan
Hyaluronic acid (HA) fillers can be removed using Hyaluronidase (Hyalase).
Usually 1 session is needed. However, for HA fillers that still remain even after 1 year, more sessions may be needed for best results.
Hope that this helps!
Warmest regards,
Dr Justin Boey
Yes, hyaluronidase can be used to dissolve away hyaluronic acid fillers, no matter how long ago they have been put in .
This is due to a hydrolytic chemical reaction which the by product is water molecules. So as long as it’s hyaluronic acid, it will become water when hyaluronidase comes into contact with it.
I have successfully dissolved a certain brand of HA that always causes avatar noses of patients from other doctors before, as they persisted for up to 2 years after injection.
There will definitely be some volume loss after the HA fillers are reabsorbed, but you will not be left worse off than prior to the HA filler injection. This is because besides volume replacement, HA fillers stimulate collagen production as well. This also helps with some volume replacement, as well as improving sagginess and skin texture. Hence even when the HA fillers are reabsorbed, you will return to a skin age/stage which is better, compared to if you had no fillers done.
Indeed, Rejuran can be combined with HA fillers (at this time just non cross-linked HAs); the HA provides the strong hydration effect which Rejuran lacks, and Rejuran provides the strong stimulatory effect that HA might not provide. The choice of the filler therefore depends first and fore-most on the lack of its cross-linking and should best be left to the doctor to decide on. You can have this done by either combining the two in a single session (manually combining two different syringes, or by using the Rejuran Hb pre-mixed syringe), or performing the treatments at different intervals.
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