How can amenorrhea due to antipsychotics be treated?

Doctor's Answer

Hi,

The best way is to simply adjust the dose or type of antipsychotic. I suggest

  1. Confirm that the cause of the hyperprolactemia is due to anti-psychotics and not due to a physical cause such as a prolactinoma, and once confirmed,
  2. Clinically assess if the person can still do well with a lower dose of the existing anti-psychotic medication and/or
  3. Switching to another antipsychotic that carries a low risk of hyper-propactinemia. E.g. Second-generation antipsychotics (SGAs), especially olanzapine, quetiapine, or even clozapine.

Best of luck,

Dr Terence Leong

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