Age has a direct correlation to the quality of the eggs in a woman.
The older the woman, particularly above 35 years, the higher the chance of the eggs losing their quality.
The quality of the eggs also dictate the quality of the embryo, and hence the success in achieving a healthy pregnancy.
In Singapore, the maximum allowable age to undergo IVF is 45 years. Personally, I feel this may need to be changed to 50 years instead, as the general health of the woman has improved this last decade and I have anecdotally seen a higher number of women above the age of 45 years being able to produce good quality eggs.