How effective is "needleless" Rejuran Healer?Aesthetic Medicine Skin, Hair & Nails Dermal Fillers
I'm interested in PDRN Rejuran Healer. I've seen an online advertisement for a "needleless"/needle-free Rejuran Healer treatment, which claims to deliver the same results without any injections, pain, or downtime. I would like to find out whether it is indeed possible to administer Rejuran Healer treatment without any injections, and how effective this method is?
Yes, I agree with Dr. Justin Boey's opinion on clarifying what your provider means by "needleless" Rejuran/PDRN/PN treatment. If it is done using a "needle-less" treatment device such as Enerjet, which is still able to deliver compounds into the skin (intradermal) using jet volumetric remodelling (JVR) technology, this is probably effective.
However, do note that most clinical studies involving Rejuran/PDRN for skin rejuvenation and wound healing properties demonstrated efficacy for injected PDRN (1). A Korean study (2) made a comparison between injected and topical PDRN (cream form) for wound healing and found the injected form to be superior to the topical form.
Intradermal injections of Rejuran/PDRN products remains to be the most efficacious way of inducing skin rejuvenation, healing and improvement (decrease) in melanin content to date (3).
The downtime involved with injected Rejuran is minimal; most patients are able to return to work/normal activity the same day. It is common to have some redness and bumpiness on the skin, but this normally subsides in a day.
Hope this helps in guiding your decision regarding a PDRN/Rejuran treatment!
Dr. Joanna Chan
1. Kui Young Park et al. Long‐chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients. Dermatologic Therapy, Jan/Feb 2016.
2. Jong Hun Lee et al. Comparison of wound healing effects between -derived polydeoxyribonucleotide (PDRN) and -derived PDRN.Arch Craniofac Surg 2018 Mar 20;19(1):20-34. Epub 2018 Mar 20.
3. Tai Kyung Noh et al. Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster. South Korea
Int J Mol Sci 2016 Sep 1;17(9). Epub 2016 Sep 1.
Dr Joanna Chan
MBBS, MMed, Dip Prac Derm
Mizu Aesthetic Clinic
8A Marina Boulevard
#B2-12 Marina Bay Link Mall, Singapore 018984
This is a good question. There are several devices that can effectively administer healing compounds into your skin using high pressured air jets. Brand names of "needle-less" treatment devices include Enerjet and Airjet.
Based on my personal experience using Enerjet for scar treatment and non-surgical face lifting, such devices can effectively administer healing compounds without "needle" injections. Common healing compounds are hyaluronic acid. Rejuran healer is also another possibility.
This "needle-less" administration of healing compounds causes minimal pain. However, don't be fooled! It is not completely free of downtime. There will be small bumps in your skin due to the high pressure jets that "inject" the healing compounds into your skin. These bumps resolve in half a day.
For treatments that have completely zero downtime, you must ask yourself if the Rejuran/Hyaluronic acid healing compounds have really been delivered effectively into your skin.
The key questions to ask your treatment provider are:
1. What is the device that they are using for "needle-less" injections?
- not every "needle-less" device is effective.
2. What is the amount of Rejuran wastage?
- for devices that do not work well, there will be wastage of product.
- if this is the case, it is more beneficial for you to rely on needle injections for more effective administration of Rejuran into your skin.
Hope that this helps!
Dr Justin Boey
Dr Justin Boey
1 Raffles Place #05-12/13
One Raffles Place (Shopping Mall)
Needless administration depends on what product you use. Hyaluronic acid for instance may be of inappropriate size for such delivery systems. Rejuran should be okay to be used with Enerjet/Airjet systems but watch out for waste of the product.
Dr Winston Lee
MBBS, MCEM, MPH
3 Simei street 6, #02-28
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