Hi TH!
Yes, as mentioned, Rejuran (a PN product) is commonly done 3-4 times, 4 weeks apart, for best results to improve skin tone, appearance of melanin and wrinkles, pore size and skin thickness (Long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients. Kui Young Park et al. Dermatologic Therapy 2015).
The above study from Korea used a protocol of 4 injections done in 2-week intervals for their clinical study, but generally most doctors are comfortable with a 2-6 week interval in between sessions.
Hope this helps!
Regards,
Dr. Joanna Chan