How safe is low dose Accutane/Isotretinoin in the long term?

It is good to hear that you have achieved good control of acne with isotretinoin. The low dose that you are taking now will reduce sebum (oil) production and maintain your condition.

From research studies done on adults, low dose isotretinoin showed no side effects to the body when the researchers did an extensive panel of blood tests on patients who took isotretinoin 20mg twice a week for 3 years.

Your dose is even lower than this so it is safe, provided that you do not have habits such as excessive alcohol intake, as that will stress your liver.

If you find that your skin condition is well maintained on this current dose, you may continue it till your late 20s when you have less oil production and acne is not a problem anymore.

Whoever is treating you with the isotretinoin regime mentioned, is at least quite forward thinking and has thrown aside the old understanding that HIGH dose = good.

The dose is so low that it is known to be fairly safe.

In fact I am taking 10mg every fortnight myself for a continued oil control and my cholesterol and liver panels are normal.

However some guys would be concerned pertaining to reproduction (whether it would increase the risk of fetal abnormalities). You can stop 3-6 months prior to your family planning and all should be good.

Meanwhile ensure your skin care products are suitable and you can eventually tail off your medications!

Winston