How can I manage the possible complications of applying tretinoin cream while on doxycycline?

Doctor's Answers 1

One of the more common issues with using tretinoin cream for acne control is skin irritation. Skin irritation is most common during the first few weeks of treatment. To manage this, consider the following strategies:

  1. Applying a lesser amount of tretinoin cream
  2. Use the tretinoin cream less frequently: 2-3 times weekly instead of nightly
  3. Apply a mild moisturizer as a base before applying the tretinoin 15 minutes later

The above strategies, alone or in combination will usually help to reduce the skin irritation from tretinoin during the initial period of starting the application of tretinoin cream and get your skin used to the medication.

Similar Questions

How long does it usually take for doxycycline to work?

For the treatment of inflammatory acne (i. e. those with painful red bumps and pus-filled bumps), doxycycline may take up to 6-12 weeks to work. Thereafter, the antibiotic should be stopped and topicals (benzoyl peroxide, adapalene and tretinoin) should be continued as maintenance therapy. Prolonged use of doxycycline indiscriminately will promote antibiotic resistance in the future. Hope this helps!

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Answered By

Dr Chin Yee Choong

Aesthetic

What should I do if doxycycline is not working for my acne?

It may be because your acne is severe and hence may need stronger treatment like isotretinoin. Another reason is non-compliance or you have not tried doxycycline long enough (usually takes 2-3 months to see significant results). Perhaps your acne is hormonal driven (in females), hence an oral contraceptive may be more beneficial for you. I would advise you to see a dermatologist for further assessment.

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