Consult Doctors. FREE.

Real Doctors, Expert Answers

Connect with Facebook Connect with Google For Doctors
By creating an account, you are indicating that you have read and accepted the DoctorXDentist Terms of Use.

Consult Doctors. FREE.

Real Doctors, Expert Answers

By creating an account, you are indicating that you have read and accepted the DoctorXDentist Terms of Use.
Registration Progress
Step 1: Indicate Topics of Interests
Step 2: Follow Relevant Doctors
Complete!
What are your interests?
Please select at least 3 interests.
NEXT
NEXT
Registration Progress
Step 1: Indicate Topics of doctors
Step 2: Follow Relevant Doctors
Complete!
Follow your favourite doctors
We found some doctors you may like. Click continue to follow them.
CONTINUE
CONTINUE

Consult Doctors. FREE.

Real Doctors, Expert Answers

Continue with Facebook Continue with Google

or

OOPS!

SOMETHING WENT WRONG.

PLEASE TRY AGAIN.

OOPS! SOMETHING

WENT WRONG.

PLEASE TRY AGAIN.

YOUR QUESTION HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL GET BACK TO YOU SHORTLY!

YOUR QUESTION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS WILL GET

BACK TO YOU SHORTLY!

YOUR QUOTE REQUEST HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL GET BACK TO YOU SHORTLY!

YOUR QUOTE REQUEST

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS WILL GET

BACK TO YOU SHORTLY!

YOUR THREAD HAS BEEN

SUCCESSFULLY CREATED.

HEAD OVER TO FORUM PAGE NOW

TO JOIN THE DISCUSSION

YOUR THREAD

HAS BEEN

SUCCESSFULLY

CREATED.

HEAD OVER TO THE FORUM PAGE NOW

TO JOIN THE DISCUSSION!

YOUR REVIEW HAS BEEN

SUCCESSFULLY SUBMITTED.

THANK YOU.

YOUR REVIEW

HAS BEEN

SUCCESSFULLY

SUBMITTED.

THANK YOU.

OOPS!

THERE IS SOMETHING

WRONG WITH YOUR EMAIL.

PLEASE TRY AGAIN.

OOPS! THERE IS

SOMETHING WRONG

WITH YOUR EMAIL.

PLEASE TRY AGAIN.

YOUR EMAIL HAS BEEN

SUCCESSFULLY SUBSCRIBED.

THANK YOU.

YOUR EMAIL

HAS BEEN

SUCCESSFULLY

SUBSCRIBED.

THANK YOU.

YOUR CONSULTATION HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL

GET BACK TO YOU SHORTLY.

YOUR CONSULTATION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS

WILL GET

TO YOU

SHORTLY.

MESSAGES TO
Admin DXD from Singapore asked a question

Should I request for a higher dose of isotretinoin if I am on a low dose isotretinoin regime?

Request answers from expert doctors:

DxD

We will distribute this question to expert doctors, and notify you about new answers.


Dr Kelvin Chua
(7 Reviews)
38 answers on DxD

Dr Terence Tan
(15 Reviews)
27 answers on DxD

Dr Lim Ming Yee
(5 Reviews)
9 answers on DxD

Hello I am a 21 yr old male with severe acne. I have recently started my course of oratane (isotretinoin) from a public hospital in Singapore. The problem is, the dermatologist i saw started me on a really low dose (10mg/day) for the first two weeks and then (20mg/day) subsequently for 2 months. I reasoned with her that I wouldn’t mind taking a higher dose as I want to experience the break out asap (before uni starts which starts 3 months later) and I wouldn’t want to take the drug over a longer period than other people would. What do you think of the low dose method? Should i go back to the dermatologist after a month to request for a much higher dosage?

DOCTOR’S ANSWER (2)

Hi Anon,

Isotretinoin is a drug that needs care on the part of the doctor when prescribing.

Firstly, it is teratogenic ( causes malformed fetuses) thus a female patient CANNOT and MUST NOT get pregnant while on the pill ( and 3-6 months thereafter to be safe).

Secondly, it has possible side effects. Disturbances of your lipid levels, renal and liver function may be possible and blood monitoring must be observed for safety’s sake.

Thirdly, it can cause really dry skin and mucous membranes ( lips) etc.

All the above occur much more often in patients on a higher dose. Therefore, I can understand why your doctor is very cautious on the dosage. I would suggest for you to be patient and follow the doctor’s advice, if not, go for a second opinion.

0 226 views 0 Doctors agree Thu Jan 25 2018 03:18:12 GMT+0000 (UTC)

Hi Anon – yes it’s true that in Sg doctors generally prefer giving lower dose – ie 10-20 mg, as opposed to in the UK where doctors tend to give 30-40 mg.

1. I reasoned with her that I wouldn’t mind taking a higher dose as I want to experience the break out asap

A breakout is actually not that common. I didn’t get one myself, neither did most of the patients I’ve started on Isotretinoin in the past. All doctors just tell you that it MAY happen as it’s a known side effect. Even if you do, don’t worry as your overall condition will rapidly improve over weeks.

2. What do you think of the low dose method?

Low dose works just as well for acne. It’s the cumulative dose that matters ie you have to take a total dosage of 1mg/kg at your bodyweight. Refer to this study:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037971/

Three months of treatment with low-dose isotretinoin (20 mg/day) was found to be effective in the treatment of moderate to severe acne vulgaris. The benefits accrued to the society from using isotretinoin outweigh the risks, and thus low-dose isotretinoin can be used in the treatment of moderate to severe acne vulgaris as an effective modality of treatment, with a low incidence of severe side effects and at a lesser cost.

I understand why you may be keen on taking a higher dose and finishing the course sooner – but same with all other meds – doctors err on the side of giving a lower dose so the medication has minimal side effects.

Having said that, see point 3.

3. Should i go back to the dermatologist after a month to request for a much higher dosage?

Yes, I don’t see why not. As a general rule, I’d always encourage you to speak directly to your doctor about your concerns/queries. Ie tell your doctor straight up why you are keen on a higher dose of isotretinoin. If he doesn’t think it’s a good idea, he will explain to you why.

Cheers

0 226 views 0 Doctors agree Thu Jan 25 2018 03:19:26 GMT+0000 (UTC)
Not the answer you're looking for? Browse other answers tagged Acne & Scars or ask your own question now FOR FREE.

Get Doctor Quotes

We promise that we'll ask our doctor friends to give you their best possible price!
Name of Treatment
Category
Budget
Full Name
Email
Contact Number
Other Information
Contact By Phone
Contact By WhatsApp