Is Ustekinumab suitable for treating psoriasis in young children? And what are the side effects?
Thank you for the question.
Ustekinumab is a biologic treatment fo psoriasis. It is approved for treating children above the age of 12 years with psoriasis. Ustekinumab is a very effective treatment for patients with moderate to severe psoriasis.
It is given as a subcutaneous injection at day 1, 1 month later and then every 3 months during the maintenance phase. Side effects of the ustekinumab injection include injection site reaction and tiredness and cold-like symptoms.
Most notably, it can suppress the immune system as it blocks specific cytokines (IL 12/23) which regulate the immune system. Utekinumab has been approved for treatement of psoriasis in Singapore since 2009. Registry data has shown that ustekinumab is safe with no major safety signals.
I have treated many psoriasis patients with Ustekinumab and have found it to be very effective and well tolerated.
There are 2 other biologics that have approval for treatment of psoriasis in children. They are Adalimumab and Etanercept.
You can discuss about these options further with your dermatologist.
Dr Colin Theng
MBBS, MRCP, MMED (Fam. Med), FAMS
Mount Alvernia Medical Centre D
820 Thomson Road #07-61