It really depends on your concerns and skin condition that you are seeking treatment for.
If it is for acne scars, then generally I would go for the stronger fractional Ablative lasers (such as the CO2 Fractional Lasers) that can penetrate deeper into the skin and break down the scar tissue more effectively. Other Ablative technologies to consider would be the Erbium lasers, Fractional RF and Microneedle RF devices.
From my understanding, both Tixel and Acnexel are similar to each other and does not penetrate deep into the skin like the other stronger fractional devices as mentioned earlier. In this respect, it may be suitable for other skin concerns that do not require intense treatment such as pores etc.
Side effects wise, I think Dr Justin has done a great summary on the side effect profile of the different technologies mentioned.
Hope this helps.
All the best!