Consult Doctors. FREE.
Real Doctors, Expert Answers
Connect with Facebook Connect with Google For Doctors
By creating an account, you are indicating that you have read and accepted the DoctorXDentist Terms of Use.
Consult Doctors. FREE.
Real Doctors, Expert Answers
By creating an account, you are indicating that you have read and accepted the DoctorXDentist Terms of Use.
Registration Progress
Step 1: Indicate Topics of Interests
Step 2: Follow Relevant Doctors
Complete!
What are your interests?
Please select at least 3 interests.
NEXT
NEXT
Registration Progress
Step 1: Indicate Topics of doctors
Step 2: Follow Relevant Doctors
Complete!
Follow your favourite doctors
We found some doctors you may like. Click continue to follow them.
CONTINUE
CONTINUE
Consult Doctors. FREE.
Real Doctors, Expert Answers
Continue with Facebook Continue with Google

or

OOPS!

SOMETHING WENT WRONG.

PLEASE TRY AGAIN.

OOPS! SOMETHING

WENT WRONG.

PLEASE TRY AGAIN.

YOUR QUESTION HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL GET BACK TO YOU SHORTLY!

YOUR QUESTION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS WILL GET

BACK TO YOU SHORTLY!

YOUR QUESTION HAS BEEN

SUCCESSFULLY SUBMITTED.

YOUR QUESTION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

YOUR ANSWER HAS BEEN

SUCCESSFULLY SUBMITTED.

YOUR ANSWER

HAS BEEN

SUCCESSFULLY

SUBMITTED.

YOUR QUOTE REQUEST HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL GET BACK TO YOU SHORTLY!

YOUR QUOTE REQUEST

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS WILL GET

BACK TO YOU SHORTLY!

YOUR THREAD HAS BEEN

SUCCESSFULLY CREATED.

HEAD OVER TO FORUM PAGE NOW

TO JOIN THE DISCUSSION

YOUR THREAD

HAS BEEN

SUCCESSFULLY

CREATED.

HEAD OVER TO THE FORUM PAGE NOW

TO JOIN THE DISCUSSION!

YOUR REVIEW HAS BEEN

SUCCESSFULLY SUBMITTED.

THANK YOU.

YOUR REVIEW

HAS BEEN

SUCCESSFULLY

SUBMITTED.

THANK YOU.

OOPS!

THERE IS SOMETHING

WRONG WITH YOUR EMAIL.

PLEASE TRY AGAIN.

OOPS! THERE IS

SOMETHING WRONG

WITH YOUR EMAIL.

PLEASE TRY AGAIN.

YOUR EMAIL HAS BEEN

SUCCESSFULLY SUBSCRIBED.

THANK YOU.

YOUR EMAIL

HAS BEEN

SUCCESSFULLY

SUBSCRIBED.

THANK YOU.

YOUR CONSULTATION HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL

GET BACK TO YOU SHORTLY.

YOUR CONSULTATION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS

WILL GET

TO YOU

SHORTLY.

MESSAGES TO
K
VIP
from Singapore asked a question

What are the treatment options for Pemphigus Vulgaris?

Request answers from expert doctors:

DxD
DxD

We will distribute this question to expert doctors, and notify you about new answers.


Dr Lee Mun Heng
Dr Lee Mun Heng
(7 Reviews)
7 answers on DxD


Dr David Ng C H
Dr David Ng C H
(3 Reviews)
20 answers on DxD
Skin, Hair & Nails

I was diagnosed with Pemphigus Vulgaris via a Biopsy in Jan 2018. I'm currently taking Prednisolone and Azathioprine to control the symptoms which are mainly in my oral cavity (gums). I have also been offered Rituximab, which I'm told is effective. However, I find this to be costly. Are there any other treatment options available for Pemphigus Vulgaris?

DOCTOR’S ANSWER (1)

Dear K,

Sorry to hear about your diagnosis of pemphigus vulgaris. Pemphigus vulgaris is an autoimmune condition where the body produces an antibody against desmoglein, which is the a protein that cements the skin cells together. This results in skin fragility and blisters and erosions on the skin or oral mucosa.

The mainstay of treatment for pemphigus vulgaris involves the use of oral steroids and immunosuppressive agents. Oral steroids have long-term side effects and usually fairly high doses of steroids are required to control this .

Other immunosuppressive agents like is azathioprine, mycophenolate mofetil and cyclophosphamide can also be used. These agents do have their own set of side effects but help to achieve reduction in the steroid doses.

Rituximab is a biologic treatment and is one of the more effective treatments for pemphigus vulgaris. It can cause immunosuppression and is  a costly treatment, but in cases of stubborn or resistant pemphigus, it is a good option.

You should ask your attending doctor about the risks/benefits of the different option. I am sure they will be more than happy to discuss this with you. 

0 251 views 1 Doctors agree Wed Mar 21 2018 11:47:46 GMT+0000 (UTC)
Not the answer you're looking for? Browse other answers tagged Skin, Hair & Nails or ask your own question now FOR FREE.

Get Doctor Quotes

Name of Treatment
Category
Budget
Full Name
Email
Contact Number
Other Information
Contact By Phone
Contact By WhatsApp