What is the significance of a raised lymphocyte count on a blood test?

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What are the implications if I am a non-responder to the hepatitis B vaccination?

Just to add on to the advice Dr Ti has provided, non-responders who have a strong family history of Hepatitis B carrier status should be aware of this entity known as "occult Hepatitis B" infection. This is a rare condition in which routine Hepatitis B surface protein test (aka HBsAg) is negative yet the person is actually a Hepatitis B carrier. This is the reason why repeated vaccination attempts will not induce antibody formation in that person since he or she is already infected with the virus.

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Dr Wai Leong Quan

Gastroenterologist

When are Hep B booster vaccinations required, and how should it be administered?

Hi Kit Kit, The vaccinations which your children received obviously have not been proven to produce any protective antibodies yet. This suggest there is either no antibody production at all (i. e. non-responder) or antibodies at too low a level to be detected by routine methods after some years. One commonly employed way to distinguish the two is to provide a booster dose given as an injection and to check for the protective antibodies 1 month later.

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Answered By

Dr Wai Leong Quan

Gastroenterologist

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