Consult Doctors. FREE.
Real Doctors, Expert Answers
Connect with Facebook Connect with Google For Doctors
By creating an account, you are indicating that you have read and accepted the DoctorXDentist Terms of Use.
Consult Doctors. FREE.
Real Doctors, Expert Answers
By creating an account, you are indicating that you have read and accepted the DoctorXDentist Terms of Use.
Registration Progress
Step 1: Indicate Topics of Interests
Step 2: Follow Relevant Doctors
Complete!
What are your interests?
Please select at least 3 interests.
NEXT
NEXT
Registration Progress
Step 1: Indicate Topics of doctors
Step 2: Follow Relevant Doctors
Complete!
Follow your favourite doctors
We found some doctors you may like. Click continue to follow them.
CONTINUE
CONTINUE
Consult Doctors. FREE.
Real Doctors, Expert Answers
Continue with Facebook Continue with Google

or

OOPS!

SOMETHING WENT WRONG.

PLEASE TRY AGAIN.

OOPS! SOMETHING

WENT WRONG.

PLEASE TRY AGAIN.

YOUR QUESTION HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL GET BACK TO YOU SHORTLY!

Disclaimer: Any answers provided are for general informational purposes only and is not a substitute for professional medical advice. If you think you may have a medical emergency, call your doctor immediately. Always seek the advice of your doctor before starting or changing treatment.

YOUR QUESTION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS WILL GET

BACK TO YOU SHORTLY!

Disclaimer: Any answers provided are for general informational purposes only and is not a substitute for professional medical advice. If you think you may have a medical emergency, call your doctor immediately. Always seek the advice of your doctor before starting or changing treatment.

YOUR QUESTION HAS BEEN

SUCCESSFULLY SUBMITTED.

YOUR QUESTION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

YOUR ANSWER HAS BEEN

SUCCESSFULLY SUBMITTED.

YOUR ANSWER

HAS BEEN

SUCCESSFULLY

SUBMITTED.

YOUR QUOTE REQUEST HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL GET BACK TO YOU SHORTLY!

YOUR QUOTE REQUEST

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS WILL GET

BACK TO YOU SHORTLY!

YOUR THREAD HAS BEEN

SUCCESSFULLY CREATED.

HEAD OVER TO FORUM PAGE NOW

TO JOIN THE DISCUSSION

YOUR THREAD

HAS BEEN

SUCCESSFULLY

CREATED.

HEAD OVER TO THE FORUM PAGE NOW

TO JOIN THE DISCUSSION!

YOUR REVIEW HAS BEEN

SUCCESSFULLY SUBMITTED.

THANK YOU.

YOUR REVIEW

HAS BEEN

SUCCESSFULLY

SUBMITTED.

THANK YOU.

OOPS!

THERE IS SOMETHING

WRONG WITH YOUR EMAIL.

PLEASE TRY AGAIN.

OOPS! THERE IS

SOMETHING WRONG

WITH YOUR EMAIL.

PLEASE TRY AGAIN.

YOUR EMAIL HAS BEEN

SUCCESSFULLY SUBSCRIBED.

THANK YOU.

YOUR EMAIL

HAS BEEN

SUCCESSFULLY

SUBSCRIBED.

THANK YOU.

YOUR CONSULTATION HAS BEEN

SUCCESSFULLY SUBMITTED.

OUR DOCTORS WILL

GET BACK TO YOU SHORTLY.

YOUR CONSULTATION

HAS BEEN

SUCCESSFULLY

SUBMITTED.

OUR DOCTORS

WILL GET

TO YOU

SHORTLY.

MESSAGES TO
Admin DXD profile picture
Admin DXD
VIP
from Singapore asked a question

Are there severe side effects of using Tretinoin cream?

Request answers from expert doctors:

DxD
DxD

We will distribute this question to expert doctors, and notify you about new answers.





Acne & Scars

hi Dr Ethan,

Thank you for writing in simple layman terms of your personal experiences for e various procedures you have done personally,

Being unaffiliated to the clinics / doctors in the blogs also give readers, like myself, confidence that e reviews are more neutral hence trustworthy.

Went to the polyclinic to request for Tretinoin cream and the doctor seemed reluctant to prescribe them to me.

She said that I have to go to a skin specialist to assess if its suitable for me.

And she cautioned me that it has severe side effects, including genetic mutations which freaked me out slightly (as am trying for a baby with my wife currently).

May I know are the side effects that severe?

Regards

DOCTOR’S ANSWER (2)

Hi DL,

As Dr Ethan correctly mentioned, topical tretinoin cream causes no severe side effects, even if you and your wife are trying for a baby. It is generally safe for use.

Common side-effects include:

  • Skin irritation, especially when they are first used. This is more likely in those with sensitive skin, resulting in stinging. Excessive use results in redness, swelling, peeling and blistering in treated areas. It may cause or aggravate eczema.
  • By peeling off the top layer of skin, they may increase the chance of sunburn.
  • Some people have reported a flare of acne in the first few weeks of treatment. This usually settles with continued use.

Hope that this helps!

Best regards,

Dr Justin Boey

Consult Doctor
0 948 views 0 Doctors agree 9 Feb 2018

Hi DL,

Thanks for your kind comments! Yes, the goal of this website is indeed to offer an unaffiliated medical perspective.

In answer to your question:

No, topical tretinoin cream causes no severe side effects, even if you and your wife are trying for a baby. In men, the only side effect is some skin sensitivity to sunlight. It definitely does not cause genetic mutations in men, or potentially your baby, if you are currently trying for a baby with your wife (ie teratogenic). This is because the skin absorption rate of tretinoin cream into your blood is way too low.

In women, even though there’s also no evidence to show it causes mutations, dermatologists and other doctors would recommend NOT to use topical tretinoin if they were trying for a baby.

You can check out a recent 2016 study on topical tretinoin, supporting what I’ve explained here:

https://www.ncbi.nlm.nih.gov/pubmed/27598619

Having said that, doctors tend to err on the side of caution when it’s a drug or medicine that they are not familiar with (myself included!). When I asked my own polyclinic friend, she also said that she would not prescribe tretinoin cream!

Both myself and a consultant dermatologist friend I double checked with would have no qualms about prescribing it, especially for men. Perhaps the polyclinic doctor was also concerned that your wife may start using it?

My guess is that if you either go to a private clinic which sees a lot of skin patients, or the NSC – you’d be much more likely to get your tretinoin cream prescription!

Consult Doctor
0 960 views 1 Doctors agree 25 Jan 2018
Not the answer you're looking for? Browse other answers tagged Acne & Scars or ask your own question now FOR FREE.

Get Doctor Quotes

Name of Treatment
Category
Budget
Full Name
Email
Contact Number
Other Information
Contact By Phone
Contact By WhatsApp