Can CALECIM® Professional Serum help with hyperpigmentation?
No, it will not help with hyperpigmentation.
Skin lightening creams that help with hyperpigmentation work by reducing the amount of melanin in the skin.
A lightening cream may have several mechanisms of action resulting in a decrease in melanin production and/or deposition in the skin cells. The different mechanisms of action include:
- Inhibiting the activity of tyrosinase e.g. hydroquinone (a major ingredient of Tri-Luma), cysteamine, arbutin, koljic acid, azelaic acid.
- Preventing tyrosinase from being activated to its functional form e.g. tretinoin (a major component of Tri-Luma), cysteamine.
- Removing the intermediate products of melanin synthesis.
- Preventing the transfer of melanin to the surrounding skin cells e.g. niacinamide
- Removing existing melanin e.g. tretinoin (a major component of Tri-Luma), exfoliating agents
- Regulation of melanocytes environment e.g. corticosteroid (a major component of Tri-Luma)
- Antioxidants e.g. vitamin C
Combining different lightening components may give a better effect if they target different parts of the pigment forming and deposition process e.g. the three major ingredients of Tri-Luma, hence augmenting the lightening capability of individual components.
You may wish to look at creams (some are over-the-counter, some are prescription medication) containing the above known lightening properties to treat your hyperpigmentation instead of Calecim serum.
Hope this helps!
Dr Chin Yee Choong
MBBS, Post Graduate Diploma (FM) Dermatology
1 Grange Road #10-03
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