Yes, hyaluronidase can be used to dissolve away hyaluronic acid fillers, no matter how long ago they have been put in .
This is due to a hydrolytic chemical reaction which the by product is water molecules. So as long as it’s hyaluronic acid, it will become water when hyaluronidase comes into contact with it.
I have successfully dissolved a certain brand of HA that always causes avatar noses of patients from other doctors before, as they persisted for up to 2 years after injection.
