This must be really troubling for you - seeing no improvement despite multiple sessions of co2 laser and microneedling.
Syringomas can be removed with CO2 lasers. When performed by a skilled doctor, there will be improvement after CO2 lasers. Usually, more than 1 session might be needed to ensure removal. However, it might regrow back.
Unfortunately, microneedling is the wrong treatment for syringoma removal.
Please seek an expert for more medical advice on this issue!
Hope that this helps!
Warmest regards,
Dr Justin Boey