Indeed as mentioned by my esteemed colleagues, isotretinoin is a good option but requires followup in view of potential side effects.
Combination of multiple treatments that include some lasers, chemical peel, oral medication and topicals can also be considered, as also already mentioned.
My 2 cents worth is that followup and continued feedback with your physician is strongly advised (as opposed to doctor hopping as many do after disappointment with initial management); doing so allows stepping up and tweaking of treatment until appropriate response is attained.
Cheers!
Shane
