Isotretinoin treatment shrinks the sebaceous glands and was felt previously that this may reduce normal wound healing after skin injury. Hence, the prudent recommendation of laser treatments that injure the skin significantly should be avoided while on isotretinoin therapy.
Subsequent retrospective studies did not show increased scarring from laser treatments while on isotretinoin therapy, leading to the considered recommendation that it is safe to perform laser treatments while on isotretinoin.
Nevertheless, it is best that you discuss with your preferred Aesthetic Doctor whether or not to proceed with laser treatment while on isotretinoin therapy. This is based on your normal wound healing pattern, the urgency of laser treatment and the aggressiveness of the laser treatment being considered.
