The best way is to adjust the antipsychotic regime by either lowering the dose or switching to another antipsychotic (one that has a lower risk of increasing prolactin levels), while maintaining the person's well being and good symptom control.
Sometimes, a combination of two antipsychotics may be needed to achieve good control of the illness while reducing the risk of hyperprolactinemia. It is also important to exclude other possible causes of raised prolactin, such as a prolactinoma, hypothyroidism, chronic liver or kidney disease.
Sometimes the raised prolactin is due to other causes rather than the antipsychotic medication. Treatment then should be focused on treating the actual underlying cause.
