Thank you for your question. Lymphoma is a malignancy of the immune system,
and is characterized by the abnormal proliferation of lymphocytes. Lymphoma
usually arises from the lymphatic system and forms large swollen lymph
nodes which eventually becomes tumour masses. Lymphomas often form silently
and without significant clinical symptoms. Some symptoms include persistent
fatigue, weight-loss, lymph node swelling, night sweats and shortness of
breath.
As with any unusual masses, a biopsy is usually indicated to determine the
histopathology of the tumour. On microscopic examination, a lymphoma will
show features of uncontrolled multiplication of lymphocytes and the
characteristics of the lymphoma have to be determined with further
immunohistochemistry or molecular testings. As there are hundreds of types
of lymphomas, with varied behaviours, the acute diagnosis of the specific
lymphoma entity is extremely crucial and important to the management. I am
proud to say that Singapore has some of the best lymphoma pathology
specialists in the world, who constantly make difficult and rare diagnosis
as well as discover new lymphoma entities.
Best regards
Dr Quah
